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Personalized Medicine for Better Treatment Outcomes

At Meadows Diagnostics, we offer Pharmacogenomics (PGx) Testing, an advanced genetic screening method that helps determine how a patient’s genes affect their response to medications. This innovative approach allows healthcare providers to personalize drug therapy, ensuring safer, more effective treatments while minimizing side effects.

Our CLIA-certified laboratory uses cutting-edge technology to analyze specific genetic markers, providing valuable insights into drug metabolism, efficacy, and potential adverse reactions.

What is Pharmacogenomics (PGx) Testing?

Pharmacogenomics is the study of how genetic variations influence drug response. Everyone processes medications differently—some may metabolize drugs too quickly, reducing their effectiveness, while others may process them too slowly, increasing the risk of toxicity. PGx testing helps identify these genetic differences, allowing doctors to choose the right medication and dosage for each patient.

By examining genes involved in drug metabolism, such as CYP2D6, CYP2C19, CYP2C9, and VKORC1, our PGx test helps healthcare providers determine:

Which medications will work best for a patient
The safest and most effective drug dosage
Which medications may cause adverse reactions

Benefits of PGx Testing

Personalized Medicine – Tailors drug therapy based on individual genetic profiles.
Reduced Trial & Error – Helps find the most effective medication faster.
Improved Drug Safety – Reduces the risk of severe side effects or adverse drug reactions.
Optimized Drug Dosage – Ensures the patient receives the correct dosage for maximum effectiveness.
Cost-Effective Treatment – Saves time and money by avoiding ineffective medications.

How PGx Testing Works

Sample Collection – A simple cheek swab or blood test is collected.
Genetic Analysis – The sample is tested in our state-of-the-art laboratory.
Comprehensive Report – Results are analyzed, providing personalized medication recommendations.
Doctor Consultation – Your healthcare provider uses the report to tailor your treatment plan.

Medications Affected by PGx Testing

Our PGx test provides insights into drug metabolism for various classes of medications, including:

Mental Health & Psychiatry

Antidepressants – Fluoxetine (Prozac), Paroxetine (Paxil), Sertraline (Zoloft)
Antipsychotics – Risperidone, Aripiprazole (Abilify), Clozapine
Mood Stabilizers – Lithium, Carbamazepine

Cardiology & Blood Thinners

Warfarin – Affects blood clotting, requiring genetic-based dosage adjustments
Clopidogrel (Plavix) – Some patients may not respond effectively due to genetic differences
Statins – Used for cholesterol management, influenced by genetic factors

Pain Management & Opioids

Codeine – Some people cannot metabolize it into its active form
Tramadol – Genetic factors determine if it provides effective pain relief
Oxycodone & Morphine – Variability in response based on metabolism genes

Oncology & Chemotherapy

5-Fluorouracil – Used for cancer treatment, response varies based on genetic makeup
Tamoxifen – Used for breast cancer treatment, metabolized differently in some patients

Who Should Get PGx Testing?

Patients taking multiple medications – Helps prevent drug interactions & side effects.
Individuals with a history of adverse drug reactions – Avoids severe complications.
Patients with chronic conditions – Ensures better management of heart disease, depression, diabetes, and more.
Cancer patients undergoing chemotherapy – Determines treatment effectiveness and risk factors.
Anyone looking for personalized medication guidance – Optimizes treatment for better health outcomes.

Why Choose Meadows Diagnostics for PGx Testing?

State-of-the-Art Technology – We use the latest molecular testing and sequencing techniques for accurate results.
Comprehensive Test Panel – Our PGx test covers multiple drug classes, ensuring detailed insights.
Board-Certified Experts – Our team of genetics and pharmacology specialists ensures highly accurate interpretations.
Fast Turnaround Time – Fast results for quicker treatment decisions.
HIPAA & CLIA Certified We follow strict privacy and industry standards to ensure the safety of your genetic data.